Substrate: Apoptosis inhibitor survivin (Adapter molecule)
Seq-ID: O15392 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-77929   INCE_HUMAN
MINT-4055407   XPO1_HUMAN
MINT-4509524   BOREA_HUMAN
MINT-4509558   AURKB_HUMAN
MINT-7969366   BECN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cobalt ion binding,
cysteine-type endopeptidase inhibitor activity,
protein heterodimerization activity,
identical protein binding,
protein homodimerization activity,
metal ion binding,
cofactor binding,
caspase inhibitor activity,
Ran GTPase binding,
microtubule binding,
chaperone binding,
zinc ion binding		 spindle,
chromosome, centromeric region,
midbody,
chromosome passenger complex,
spindle microtubule,
cytoplasm,
cytosol,
centriole,
cytoplasmic microtubule,
interphase microtubule organizing center,
nuclear chromosome		 cytokinesis,
positive regulation of mitotic cell cycle,
apoptosis,
anti-apoptosis,
chromosome segregation,
establishment of chromosome localization,
negative regulation of caspase activity,
positive regulation of exit from mitosis,
mitosis,
spindle checkpoint,
G2/M transition of mitotic cell cycle,
protein complex localization,
cell division
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 34 NWPFLEGCACTPERMAEAGFI CDK1 11861764
LTP
1.00
 MOD_CDK_SPxK_1
 - BIR
0.19
 2RAW 10.96%
T 34 NWPFLEGCACTPERMAEAGFI CDK1 11069302
LTP
1.00
 MOD_CDK_SPxK_1
 - BIR
0.19
 2RAW 10.96%
T 117 ERAKNKIAKETNNKKKEFEET Aurora B 14610074
LTP
0.68
 - COIL
0.56
 2RAW 50.68%

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